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A 2025 randomized, double-blind, placebo-controlled trial published in Clinical Nutrition found that 15 mg/day of hydroxytyrosol improved antioxidant and anti-inflammatory status in overweight individuals with prediabetes over 16 weeks, while preserving insulin sensitivity (Moratilla-Rivera et al., 2025)

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Una complicacin mas temible es la cetoacidosis diabtica (CAD) normoglicmica que se ha descrito en algunos pacientes, provocada por la reduccin en las dosis, por mejora de la glicemia insulino-independiente

Physiol Behav 2004;83:645-51