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doi: 10.1001/jamanetworkopen.2024.13172 146 KimCRossJSJastreboffAMMeekerDFreedmanHKrumholzHMet al

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Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor

A synergistic effect was also observed, wherein the values of duration of the added mean durations of both monotherapies independently was substantially less than the mean duration of multiple agent therapies, all at the same dose levels for each component

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