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Verma, M

Oxidative stress is involved in the pathophysiology of PD as excessive production of reactive oxygen species (ROS) contributes to dopaminergic neuronal damage, which is susceptible to oxidative injury due to high metabolic activity and dopamine metabolism

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Excess ROS activates inflammasome pathways, including NLRP3 inflammasome, promoting pyroptosis, an inflammatory form of cell death (Fig

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Cancer cells that were intrinsically sensitive to As 2 O 3 contained lower levels of GSH, whereas resistant cancer cells contained higher levels of GSH