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Current treatment guidelines for severe symptomatic chronic hyponatremia recommend empiric intervention with intravenous 3% NaCl to increase serum sodium levels by 46 mmol/L within the first 24 h 3,4,6,7,8,9

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The purpose of the study aims to examine the effect of inhalation hydrogen gas on the pathophysiology of a mouse model of asthma

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The remaining 3 studies, scored eight and nine, indicating high-quality studies with low risk of bias (Table 5)