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Carbohydrate-heavy meals can trigger severe postprandial tachycardia (a rapid heart rate after eating) in POTS patients
For instance, a study in the International Journal of Colorectal Disease showed that patients recovering from bowel surgery tolerated Ipamorelin well when given the peptide twice daily for 7 days: 117 patients were enrolled, of whom 114 patients composed the safety and modified intent-to-treat populations
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications originally developed for type 2 diabetes management and now increasingly prescribed for weight management
Shortly afterwards, in October 1964, Harold Elrick and his colleagues at the University of Colorado Medical School, independently showed that oral doses of glucose produced significantly higher levels of plasma insulin than when given by intravenous injection (Elrick, Stimler, Arai)
Further work is needed to elucidate the mechanism(s) by which this occurs
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