This result was replicated in a similar but larger investigation ( N = 1,735) comparing all available GLP-1RAs versus non-GLP-1RA antidiabetics, with this antidepressant association possibly correlating with changes in markers of systemic inflammation (that is, high-sensitivity C-reactive protein) 192
healthcare professionals should review concomitant diabetes medicines before and during treatment Delayed gastric emptying as with other GLP-1-based therapies, retatrutide may slow gastric emptying, which could affect the absorption of some oral medicines
Poor Prescription Management Means More Work for Nutritionists Managing GLP-1 Side Effects There are also an unfortunately high number of cases emerging where physicians are prescribing GLP-1 therapies without consulting nutritionists or adequately assessing their patients for eating disorders
However, some healthcare professionals and pharmacies may offer compounded versions instead
Effects of GLP-1 receptor activation on a pentylenetetrazolekindling rat model
For a comprehensive list of beginner mistakes beyond GLP-1 specifically, see our common peptide mistakes beginners make guide and the getting started with peptides overview