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Select an injection site (abdomen, thigh or upper arm) and clean it with a fresh alcohol swab, letting it dry fully [11]

Chen G, et al

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Drug interactions : Both supplements may interact with medications: Berberine and diabetes medications : Berberine can lower blood glucose and may potentiate the effects of metformin, sulphonylureas, or insulin, increasing the risk of hypoglycaemia

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In the 48-week phase 2 trial published in the New England Journal of Medicine, retatrutide at the 12mg weekly dose produced an average body weight reduction of 24.2%