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Despite GLP-1 concentration being higher in the fundus than the antrum, its release ex vivo upon IBMX stimulation increases to the same extent in both the fundus and antrum, suggesting a significant contribution to both portal and gastric GLP-1 (Ribeiro-Parenti et al., 2021)

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NPM-139, which utilizes Vivanis NanoPortal platform technology, is under development for chronic weight management

One thing to know straight away: you cannot eat your way to a therapeutic dose of berberine