Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione
Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3
Oxid Med Cell Longev (2016) 2016:19
Since glucocorticoids are known to mediate inhibition of NF-kB (beneficially modulated by certain antioxidants such as thiols), adjunctive therapy with an effective thiol donor (e.g., NAC or SAMe) and vitamin E may optimize control of inflammatory mediator release and cell response as compared to pure immunomodulatory treatment or therapy limited to antioxidants
Hyperreactivity or asthma attacks are frequently the cause of death for people with asthma due to oxygen deprivation and respiratory distress from mucus obstruction (Yoshida et al., 2020)
Furthermore, it mitigated the aggravating effects of L-NAME and L-arginine on convulsions, suggesting a potential non-NO-system involvement in its therapeutic effects