Carbone G, Wilson A, Diehl SA et al (2013) Interleukin-6 Receptor Blockade Selectively Reduces IL-21 Production by CD4 T Cells and IgG4 Autoantibodies in Rheumatoid Arthritis
If authorized, these products could introduce early competition in the rapidly expanding market for treatments targeting type 2 diabetes and obesity
Roles of increased glycaemic variability, GLP-1 and glucagon in hypoglycaemia after Roux-en-Y gastric bypass
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ALA acts as a cofactor for pyruvate dehydrogenase and -keto-glutarate dehydrogenase activity (Schmidt et al., 1994), and is also required for the oxidative decarboxylation of pyruvate to acetyl-CoA, a critical step bridging glycolysis and the citric acid cycle (Reed, 1998)