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Diabet Med (1989) 6(2):10311.10.1111/j.1464-5491.1989.tb02096.x 271 ParkinsonCDrakeWMRobertsMEMeeranKBesserGMTrainerPJ

Convincing evidence for the association of oxidative/nitrosative stress and SLE diseases has been shown by increased levels of validated biomarkers of oxidative stress in the disease

Oxidative stress can cause damage to DNA, proteins and lipids

Mitochondria, as the major site of oxidative reactions, must maintain sufficient levels of GSH to perform protective and biosynthetic functions 2

First, factors such as comorbidities, diet, and lifestyle were not routinely reported in the trials and may have influenced the treatment response

Relationships with activation markers of T cells, B cells, and monocytes