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L Glutathione is a linked tripeptide ( L glutamyl L cysteinylglycine) and the most abundant low-molecular-weight thiol in cells

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We hypothesize that the influence of SFN on the gut microbiota is at least partly related to the effects on their habitat, i.e., the gut such as (i) alleviation of oxidative stress and inflammation in the intestine, (ii) increase of the expression of tight junction proteins, preventing excessive intestinal permeability and invasion of luminal bacteria, and (iii) promotion of gut detoxification capability via increase of activity of phase II detoxification enzymes such as GSTs

Researchers believe this effect may involve: Increased epithelial cell migration Enhanced tissue regeneration Protection of intestinal lining integrity These mechanisms may explain why the peptide has been studied as a possible therapeutic agent for gastrointestinal injury models

C., Ervin, A

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