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Now, inspired by the mitochondria-focused genetic interaction map in Saccharomyces cerevisiae 11 and the known influence of environment on genetic interactions 12 , we sought a dual genetic perturbation approach to probe the human SLC25 transporters under different metabolic states 13

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The emergence of oral GLP-1s, once-monthly injectables, dual- and triple-receptor targets and combination therapies has enhanced patient convenience, improved adherence and broadened clinical utility, bringing healthcare practitioners more options for individualized treatment

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