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Key effects of GLP-1 medications Encourage insulin release when blood sugar rises Slow stomach emptying to improve digestion and increase fullness Reduce appetite Lower post-meal glucose spikes Support sustainable weight loss efforts Because many GLP-1 drugs come with high monthly costs, people often use price comparison resources to get a sense of price ranges before deciding which option to pursue

One key difference is that the doses used for weight loss are higher, which allows it to work on the brains receptors

[4] [10] Data from a phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated that gastrointestinal side effects were among the most commonly reported adverse events with retatrutide, particularly at higher doses

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