Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewings sarcoma: a phase 1 expansion cohort study
The glycosuria induced by these medications creates a glucose-rich urinary environment that can promote genital mycotic infections (thrush) in 1015% of patients, particularly women
As previously shown, DPI induced progressive cell death over the three-day observation period, which was significantly mitigated by downregulation of MYCN (16) ( Figure 1C )
Proc Natl Acad Sci U S A 105(43):1676716772
Here we reveal unexpected overlap between signalling and regulation of the glucagon-like peptide-1 (GLP-1) receptor by the non-peptide agonist, PF 06882961, and GLP-1 that was not observed for another compound, OWL-833
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