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A non-responder stopping rule was applied at 12 weeks, defined as failure to achieve 5% weight loss from baseline

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In each of these studies, treatment with RYALTRIS resulted in a statistically significant greater decrease from baseline in the overall RQLQ(S) than placebo (LS mean difference from placebo for Study 1: -0.5 [-0.8, -0.3]

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This results in the urine becoming more concentrated (or urine osm)

A DVT is diagnosed using: Blood tests