After 2 weeks, increase dose as tolerated to 20 mcg SubQ once daily Tirzepatide (Mounjaro) Initial dose: 2.5 mg SubQ once weekly for 4 weeks, then increase to 5 mg SubQ once weekly
Hair loss during GLP-1 medication use is a reported concern, though it is not a direct drug effect
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Patients typically use physical therapy to strengthen muscles (for joint support), bracing or orthotics to stabilize loose joints, analgesic medications (NSAIDs, acetaminophen, or stronger pain relievers) for pain control, and lifestyle modifications to avoid injury
Neurotoxic -amyloid oligomers cause mitochondrial dysfunction-the trigger for PANoptosis in neurons
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