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ES831000: 4-Methylumbelliferyl α-L-Idopyranosiduronic Acid 2-Sulfate (Disodium Salt) Pack Size:5 mg enzymatic cleavage releases 4-methylumbelliferone

SKU: 53608505457

4.1
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Description

enzymatic cleavage releases 4-methylumbelliferone

89 / HHV1-gB(UniProt ID P08665) synthetic glycopeptide HSV1-gB fragment (Thr53-Pro56

and the construction of probes for galactose-recognizing proteins

/ Fmoc-Thr((Ac)7-Lac-β-D)-OH / Fmoc-Thr(β-D-Lac)-OH

The sugar hydroxyl groups are protected as three acetate esters (Ac3)

ES831000: 4-Methylumbelliferyl α-L-Idopyranosiduronic Acid 2-Sulfate (Disodium Salt) Pack Size:5 mg enzymatic cleavage releases 4-methylumbelliferoneC16H14O12SNa2 476. 3 A 4 methylumbelliferyl glycoside of 2 O sulfated L iduronic acid (IdoA2S), supplied as the disodium salt. This is the standard fluorogenic substrate for iduronate 2 sulfatase (IDS), the lysosomal sulfatase deficient in Hunter syndrome (mucopolysaccharidosis type II), used in IDS activity assays for enzyme replacement therapy research, diagnostic screening, and inhibitor activator studies. Two sequential enzymatic reactions are

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