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We show that GLP-1(2836) entered mouse caSMCs and ECs by macropinocytosis and activated sAC, as evidenced by the increased production of cAMP in caSMCs from WT but not sAC / mice

PubMed ID: 11673763 Mor MI et al

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Interestingly, the up-regulation of M2 markers demonstrates that Ex-4 promotes the polarization toward the anti-inflammatory M2 phenotype post MCAO in both aged T2DM/obese and normal mice, implying a new mechanism based on Ex-4- mediated neuroprotective efficacy (135)

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In Malaysia, GLP-1 Injection cost around RM500-RM 600 per pen