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Description

Mechanism of Action: qualitatively similar to dextroamphetamine compared to amphetamine, the methyl side group present in methamphetamine results in a higher lipid solubility, greater penetration of the blood brain barrier, higher potency with respect to dopamine release, longer half life, and higher potential for abuse and neurotoxicity due to oxidative stress (Yamamoto & Raudensky, 2008

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The two compounds work through separate pathways, minimizing direct interference

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Consent to Participate and Publish The requirement for patient-informed consent was waived because this was a retrospective study of medical records that did not involve patient participation

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