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Removing a medication that works for an entire population isnt an accepted approach for other cardiometabolic conditions like diabetes or hypertension, and obesity shouldnt be any different

Fragment: C78H125N23O23S2

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23 Supplementation of 1 mg daily is recommended for patients with specific risk factors (e.g., bariatric/gastric surgery patients, those with severe malnutrition, chronic alcohol use, chronic hemolytic anemia and conditions with high cell turnover, and use of antimetabolite medications such as methotrexate)

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Finally, mucosal impedance testing is another tool to directly evaluate mucosal integrity, although most studies are limited to the esophagus