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In effect, retatrutide tells the body to eat less (GLP-1 and GIP) while also burning more (glucagon)

Last reviewed: June 25, 2026 Last updated: June 25, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

If possible, be prepared to answer questions about: When the reactions first started How long youve experienced them If theyve gotten worse or stayed the same What the reactions look or feel like (e.g