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Other studies performed in mice demonstrate that pancreatic Y1-R activation facilitates the trans-differentiation of -cells into -cells, thereby improving insulin sensitivity 21

In order to have a better understanding of ROS testis neutralization or limitation by the antioxidant systems, we summarize the major pathways of ROS generation and the mechanistic antioxidative defense in Figure 1

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Witschi A, Reddy S, Stofer B, Lauterburg B H, The systemic availability of oral glutathione, European Journal Clinical Pharmacology

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