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5 / A 4-methylumbelliferyl α-glycoside of a GlcNAcβ1-4Man disaccharide
The sugar hydroxyl groups are protected as seven acetate esters (Ac7)
the simplest mucin-type O-glycan and a tumor-associated carbohydrate antigen
6-tetra-O-acetyl-β-D-glucopyranosyl)-L-threonine
O-glycosylation
AG124000: α-D-GalNAc-Ethyl-Azide Pack Size:250 mg 5 / A 4-methylumbelliferyl α-glycosideC10H18N4O6 290. 27 An D N acetylgalactosamine ( D GalNAc) ligand equipped with an azide functionalized linker through a short ethyl spacer. The terminal azide can be covalently coupled to alkyne partners via copper catalyzed azide alkyne cycloaddition (CuAAC), or to dibenzocyclooctyne (DBCO) and related strained alkynes using copper free click chemistry. This compound enables the construction of hepatocyte targeted therapeutics and research tools that
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