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Understanding keloid pathobiology from a quasi-neoplastic perspective: less of a scar and more of a chronic inflammatory disease with cancer-like tendencies

It is also obtained through diet

The major sources are meats, dairy products, and some fish

In practical terms, intact skin blocks these molecules before they can reach circulation

Journal of Human Hypertension volume 16: 453457

A complementary axis involves transcriptional reinforcement of antioxidant programs, including NFE2 like BZIP transcription factor 2 (NFE2L2, also known as NRF2) signaling, which increases GPXs and further suppresses ROS-driven inflammasome activation 58