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These drugs work by mimicking a hormone in the intestines, stimulating the release of insulin and reduce blood glucose after the patient has eaten a meal

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Insulin is a fat storing hormone

Regulation of PRPP synthase The enzyme, PRPP synthetase, is activated by Pi (inorganic phosphate) and inhibited by the purine bases adenine and guanine

I.KoychevI.et al (2025)

Glucagon-like peptide 1 (736) amide (GLP-1) and exendin-4 stimulate serotonin release in rat hypothalamus