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7, 11 Most cases resolve spontaneously, but pain can persist for several months or even years

In doxorubicin-induced cardiotoxicity, PSG-1 confers cardioprotection by selectively suppressing the mitochondrial intrinsic apoptotic pathwayevidenced by enhanced MnSOD activity, preservation of mitochondrial membrane potential, inhibition of mitochondrial permeability transition pore (mPTP) opening, and attenuated cytochrome c release into the cytosol (Ubaidillah et al., 2016)

(Tokyo, Japan), which may have a commercial interest in the serum product

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Consent for publication The authors declare that they have no competing interests