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3g, Extended Data Fig 4c,d)

In addition to being an antioxidant itself, glutathione is also a cofactor for several other antioxidant enzymes1-3

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Those with Poor Diets: Individuals who dont consume a balanced diet may be at risk of vitamin B12 deficiency

A study found that the NRF2-KEAP1 complex keeps shuttling constantly between the cytoplasm and the nucleus, and in the nucleus, the nuclear protein prothymosin competes for NRF2 binding to KEAP1 and enables the liberated NRF2 to activate NRF2 target genes [15]

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