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Neither class produces lasting benefit after discontinuation for most patients

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One 2023 study in Circulation even found that clearing senescent cells, including with FOXO4-DRI, worsened pulmonary hypertension in rodents

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9-Tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis study

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