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Conversely, ferroptosis inhibitors, such as Lip-1, Fer-1, and DFO, have been shown to improve disease symptoms and extend the diminution of the colon length in dextran sulfate sodium (DSS)-induced colitis in mice, indicating that suppression of ferroptosis has a positive effect on IBD (140142)

Wall Street estimates the GLP-1 drugs could net the company $13.5 billion in 2024

The biggest challenge seems to be patient retention

Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass

This is again not shutting down your natural pathways when you become desensitized to their effect, but rather, like alcohol, you build up a tolerance