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These effects generally indicate either starting doses too high or individual sensitivity

Due to changes in your digestive system and how your body metabolizes drugs, you may need a lower dose than what's typically recommended on the packaging

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Jabbour AM, Heraud JE, Daunt CP, Kaufmann T, Sandow J, OReilly LA, Callus BA, Lopez A, Strasser A et al (2009) Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim

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