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5.4 Combination of systemic therapy and immunotherapy in HCC Before ICI immunotherapy had modified the management of HCC in the past few years, around 50% of patients with HCC received systemic therapies, generally, sorafenib or lenvatinib in the first line, followed by regorafenib, cabozantinib or ramucirumab as the second

Enhance absorption rates can increase by up to 98%

The Warburg effect mediator pyruvate kinase M2 expression and regulation in the retina

2 ) (Genazzani et al., 2011)

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Nervup Injection is generally safe and does not usually cause any common side effects