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This acid-base disturbance often accompanies hypokalemia and hypochloremia (low chloride)

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Chronic, untreated metabolic acidosis may increase the risk for nephrolithiasis or nephrocalcinosis and may also result in osteomalacia (referred to as rickets in pediatric patients) and/or osteoporosis with an increased risk for fractures

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According to some references, using MB alongside insulin or oral hypoglycemic agents may necessitate caution, as MB might affect carbohydrate metabolism or stress responses

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