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A systems immunology perspective on gout pathogenesis and its precision-targeted treatment strategies

The bone effects of amylin analogues also deserve investigation, as these drugs not only bind the amylin receptors AMY1R, AMY2R, and AMY3R, but also the calcitonin receptor, raising the possibility of direct effects on bone metabolism [10]

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This leads to a more gradual rise in blood sugar levels after eating and can also contribute to a feeling of fullness and reduced appetite