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This escalation approach improves tolerability while identifying the minimum effective dose for each individual
However, some individuals may experience: Injection site reactions such as mild redness, itching, or swelling Water retention or mild fluid buildup, particularly in the early weeks Joint discomfort or stiffness, which often resolves as the body adjusts Tingling or numbness in the hands or feet (less common) Elevated blood glucose levels in individuals predisposed to insulin resistance It is worth noting that tesamorelin should not be used by individuals with active cancer, those who are pregnant, or patients with hypersensitivity to its components
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Administration Methods Subcutaneous (SubQ) Injection: Typically done in the fatty tissue of the abdomen or near the site of injury for localized healing
In UK practice, monitoring is primarily based on clinical response rather than routine blood tests, as post-treatment serum B12 measurements can be misleadingly high and may not reflect tissue levels
