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These include: Nausea (reported in approximately 24-30% of patients) Diarrhea (18-24% of patients) Vomiting (8-21% of patients) Constipation (16-24% of patients) Abdominal pain or discomfort Decreased appetite Dyspepsia/GERD (gastroesophageal reflux disease) Dizziness Hair loss (alopecia) These effects are typically most pronounced during dose escalation and often diminish over time as the body adjusts to the medication

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In addition, we saw a similar increase in plasma active GIP levels in response to linagliptin in PDX1Cre control mice and Gcg RA PDX1Cre mice (Fig

A systematic rotation schedule should ensure no site receives repeated injections within 24-48 hours

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