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Despite both being GLP-1 agonists, liraglutide and semaglutide differ significantly in potency, dosing frequency, and clinical outcomes

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As an investigational compound, it has not yet received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and its use remains confined to clinical research settings

It suppresses the release of glucagon, a hormone that signals the liver to produce more glucose

That variation is driving a lot of interest in understanding the underlying biology. Researchers hope that, over time, they will be able to predict who will benefit most based on genetics, environment and other biological factors

Even at lower doses, GLP-1 compounds can help regulate appetite, curb cravings, and support balanced metabolic function