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In a double-blind, placebo-controlled, dose-titration study, 1 to 3 g/day of oral propionyl-L-carnitine for 24 weeks was well tolerated and improved maximal walking distance in patients with intermittent claudication (64)

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It has been shown to have higher resistance to ferroptosis induced by GPX4 deletion than M2 (50)

Similarly, SCFA-producing genera were consistently depleted in male rodent models exposed to PS-MPs and PS-NPs including Faecalibaculum and Akkermansia (Yang J.-Z

Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and child outcomes