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10.1053/j.gastro.2015.09.039 66 KumarV.SethiB.StallerD

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Additionally, myofibroblast contraction, tissue stiffening and aberrant tensile forces in the ECM activate latent TGF- from ECM stores, thereby inducing e.g., Smad2/3-signaling and contributing to fibrosis (147)

Other effects of NAC have also been described, such as modulating the immune and inflammatory response, counteracting the thrombotic state, and having an antiviral effect