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Like with any medication or supplement, it may take time for your system to adapt to the influx of B12

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The fluid retention can also increase blood pressure and stress the cardiovascular system

It lets nutrients pass through, while keeping most microbes and toxins on the inside

However, absorption often declines with age and can be impaired by digestive conditions (such as IBS, Crohns, or coeliac disease) and by certain medications (for example, long-term use of proton pump inhibitors)