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Eur J Immunol (2010) 37(1):S3445

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The authors also propose that the classification can be used to assist treatment decision making, with surgical dbridement and possible repair recommended for grade 4 tears that fail 6 months of conservative treatment (Table 1)

Advanced / Aggressive Approach (2 mL = ~2,500 mcg/mL) Reconstitute: Add 2.0 mL bacteriostatic water to one 5 mg vial final concentration: ~2,500 mcg/mL