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KOA is characterized by articular cartilage injury, accompanied by synovitis and subchondral bone sclerosis [5]

doi: 10.3389/fphar.2023.1187797 Received 16 March 2023 Accepted 25 October 2023 Published 13 November 2023 Volume 14 - 2023 Edited by Runyue Huang, Guangzhou University of Chinese Medicine, China Reviewed by Cong-En Zhang, Capital Medical University, China Guangrui Huang, Beijing University of Chinese Medicine, China Updates Copyright 2023 Xu, Peng, Ma, Xie, Li, Wang, Guo, Nan, Wang, Li, Xu and Gong

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IGF-1 has insulin-like activity, and hypoglycemia is the most reproducible acute side effect community sources describe