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33 / A β-D-glucose ligand equipped with an azide handle through a hydrophilic PEG3 spacer
Tumour-associated carbohydrate antigen (TACA)
5-Diamino-2-(6-carboxy-3
enzymatic cleavage releases 4-nitrophenol
O-glycosylation with Sialyl TF
PE134000: α-GalNAc-PEG3-Azide label-new 33 / A β-D-glucose ligandC14H26N4O8 378. 38 An D N acetylgalactosamine (GalNAc) ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the
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